A new international study led by IMAGINE-ID researchers Dr Samuel Chawner and Prof Marianne van den Bree has been published in the American Journal of Psychiatry. The research focused on autism in individuals with genetic conditions.
Autism assessment data was collected from across Europe and America, and included data from the IMAGINE-ID cohort. The research focused on 16p11.2 deletion, 16p11.2 duplication, 22q11.2 deletion, and 22q11.2 duplication genetic conditions and found many individuals with these conditions met autism diagnosis criteria. Furthermore, individuals with genetic conditions who did not meet strict autism criteria still experienced clinically important autism symptoms, indicating that clinicians need to look beyond autism diagnosis when considering the needs of children with genetic conditions.
Next, it was investigated whether different genetic conditions lead to different types of autism genetic condition. Although each genetic condition had its own unique autism symptom profile, there was a lot of overlap indicating that clinical support for autism could be grouped for different genetic conditions.
We are grateful to all the families who took part to make this research happen.